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Structure paper

TitleStructural insights into IFIT1 dimerization and conformational changes associated with mRNA binding
Journal, issue, pagesTo Be Published
Publish dateJun 15, 2017 (structure data deposition date)
AuthorsAbbas, Y.M. / Martinez-Montero, S. / Cencic, R. / Pelletier, J. / Damha, M.J. / Pawelek, P.D. / Nagar, B.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.65 - 2.79 Å
Structure data

PDB-5w5h:
Human IFIT1 dimer with m7Gppp-AAAA
Method: X-RAY DIFFRACTION / Resolution: 2.79 Å

PDB-5w5i:
Human IFIT1 dimer with PPP-AAAA
Method: X-RAY DIFFRACTION / Resolution: 2.65 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • unidentified (others)
KeywordsRNA binding protein/RNA / mRNA cap / N7-Methylguanosine-triphosphate RNA / tetratricopeptide repeat / RNA binding protein / RNA binding protein-RNA complex / triphosphate RNA

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