+Search query
-Structure paper
Title | Human GLP-1 receptor transmembrane domain structure in complex with allosteric modulators. |
---|---|
Journal, issue, pages | Nature, Vol. 546, Page 312-315, Year 2017 |
Publish date | Apr 5, 2017 (structure data deposition date) |
Authors | Song, G. / Yang, D. / Wang, Y. / de Graaf, C. / Zhou, Q. / Jiang, S. / Liu, K. / Cai, X. / Dai, A. / Lin, G. ...Song, G. / Yang, D. / Wang, Y. / de Graaf, C. / Zhou, Q. / Jiang, S. / Liu, K. / Cai, X. / Dai, A. / Lin, G. / Liu, D. / Wu, F. / Wu, Y. / Zhao, S. / Ye, L. / Han, G.W. / Lau, J. / Wu, B. / Hanson, M.A. / Liu, Z.J. / Wang, M.W. / Stevens, R.C. |
External links | Nature / PubMed:28514449 |
Methods | X-ray diffraction |
Resolution | 2.7 - 3 Å |
Structure data | PDB-5vew: PDB-5vex: |
Chemicals | ChemComp-97Y: ChemComp-OLC: ChemComp-OLA: ChemComp-HOH: ChemComp-97V: |
Source |
|
Keywords | SIGNALING PROTEIN / GPCR / class B / 7TM domain / treatment of type 2 diabetes |