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Structure paper

TitleStructural basis for high-affinity fluorophore binding and activation by RNA Mango.
Journal, issue, pagesNat. Chem. Biol., Vol. 13, Page 807-813, Year 2017
Publish dateMar 7, 2017 (structure data deposition date)
AuthorsTrachman, R.J. / Demeshkina, N.A. / Lau, M.W.L. / Panchapakesan, S.S.S. / Jeng, S.C.Y. / Unrau, P.J. / Ferre-D'Amare, A.R.
External linksNat. Chem. Biol. / PubMed:28553947
MethodsX-ray diffraction
Resolution1.7 Å
Structure data

PDB-5v3f:
Co-crystal structure of the fluorogenic RNA Mango
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

Chemicals

ChemComp-K:
Unknown entry

ChemComp-74G:
4-{[(2S)-3-{2,16-dioxo-20-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]-6,9,12-trioxa-3,15-diazaicosan-1-yl}-2,3-dihydro-1,3-benzothiazol-2-yl]methyl}-1-methylquinolin-1-ium

ChemComp-PO4:
PHOSPHATE ION

ChemComp-HOH:
WATER

Source
  • synthetic construct (others)
KeywordsRNA / quadruplex fluorescent RNA

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