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TitleA Macrocyclic Peptide Ligand Binds the Oncogenic MicroRNA-21 Precursor and Suppresses Dicer Processing.
Journal, issue, pagesACS Chem. Biol., Vol. 12, Page 1611-1620, Year 2017
Publish dateFeb 27, 2017 (structure data deposition date)
AuthorsShortridge, M.D. / Walker, M.J. / Pavelitz, T. / Chen, Y. / Yang, W. / Varani, G.
External linksACS Chem. Biol. / PubMed:28437065
MethodsNMR (solution)
Structure data

PDB-5uzt:
Structure of wild type pre-miR21 apical loop
Method: SOLUTION NMR

PDB-5uzz:
Structure of wild type pre-miR21 apical loop
Method: SOLUTION NMR

Source
  • homo sapiens (human)
  • synthetic construct (others)
KeywordsRNA / microRNA miR-21 oncomiR pre-miRNA / TRANSPORT PROTEIN/RNA / TRANSPORT PROTEIN-RNA complex

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