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-Structure paper
| Title | USP7 small-molecule inhibitors interfere with ubiquitin binding. |
|---|---|
| Journal, issue, pages | Nature, Vol. 550, Page 534-538, Year 2017 |
| Publish date | Feb 8, 2017 (structure data deposition date) |
 Authors | Kategaya, L. / Di Lello, P. / Rouge, L. / Pastor, R. / Clark, K.R. / Drummond, J. / Kleinheinz, T. / Lin, E. / Upton, J.P. / Prakash, S. ...Kategaya, L. / Di Lello, P. / Rouge, L. / Pastor, R. / Clark, K.R. / Drummond, J. / Kleinheinz, T. / Lin, E. / Upton, J.P. / Prakash, S. / Heideker, J. / McCleland, M. / Ritorto, M.S. / Alessi, D.R. / Trost, M. / Bainbridge, T.W. / Kwok, M.C.M. / Ma, T.P. / Stiffler, Z. / Brasher, B. / Tang, Y. / Jaishankar, P. / Hearn, B.R. / Renslo, A.R. / Arkin, M.R. / Cohen, F. / Yu, K. / Peale, F. / Gnad, F. / Chang, M.T. / Klijn, C. / Blackwood, E. / Martin, S.E. / Forrest, W.F. / Ernst, J.A. / Ndubaku, C. / Wang, X. / Beresini, M.H. / Tsui, V. / Schwerdtfeger, C. / Blake, R.A. / Murray, J. / Maurer, T. / Wertz, I.E. |
 External links | Nature / PubMed:29045385 |
| Methods | X-ray diffraction |
| Resolution | 2.23 - 2.84 Å |
| Structure data |  PDB-5uqv:  PDB-5uqx: |
| Chemicals |  ChemComp-8JM:  ChemComp-8JP:  ChemComp-HOH: |
| Source |
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 Keywords | HYDROLASE/HYDROLASE INHIBITOR / HAUSP / USP7 / SBDD / HYDROLASE-HYDROLASE INHIBITOR complex |
homo sapiens (human)