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Title | Structural characterization of human Vaccinia-Related Kinases (VRK) bound to small-molecule inhibitors identifies different P-loop conformations. |
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Journal, issue, pages | Sci Rep, Vol. 7, Page 7501-7501, Year 2017 |
Publish date | Aug 31, 2010 (structure data deposition date) |
![]() | Counago, R.M. / Allerston, C.K. / Savitsky, P. / Azevedo, H. / Godoi, P.H. / Wells, C.I. / Mascarello, A. / de Souza Gama, F.H. / Massirer, K.B. / Zuercher, W.J. ...Counago, R.M. / Allerston, C.K. / Savitsky, P. / Azevedo, H. / Godoi, P.H. / Wells, C.I. / Mascarello, A. / de Souza Gama, F.H. / Massirer, K.B. / Zuercher, W.J. / Guimaraes, C.R.W. / Gileadi, O. |
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Methods | X-ray diffraction |
Resolution | 2 - 2.4 Å |
Structure data | ![]() PDB-3op5: ![]() PDB-5ukf: ![]() PDB-5uu1: ![]() PDB-5uvf: |
Chemicals | ![]() ChemComp-REB: ![]() ChemComp-EDO: ![]() ChemComp-GOL: ![]() ChemComp-HOH: ![]() ChemComp-8E1: ![]() ChemComp-PO4: ![]() ChemComp-CL: ![]() ChemComp-PEG: ![]() ChemComp-7DZ: |
Source |
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![]() | TRANSFERASE / Adenosine Triphosphate / Amino Acid Sequence / Binding Sites / Catalytic Domain / Models / Molecular / Molecular Sequence Data / Phosphotransferases / Protein Conformation / Protein Folding / Surface Entropy Reduction / Structural Genomics / Structural Genomics Consortium / SGC / Transferase/Transferase Inhibitor / protein kinase domain / Transferase-Transferase Inhibitor Complex |