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Structure paper

TitleModulating the DNA polymerase beta reaction equilibrium to dissect the reverse reaction.
Journal, issue, pagesNat. Chem. Biol., Vol. 13, Page 1074-1080, Year 2017
Publish dateJan 9, 2017 (structure data deposition date)
AuthorsShock, D.D. / Freudenthal, B.D. / Beard, W.A. / Wilson, S.H.
External linksNat. Chem. Biol. / PubMed:28759020
MethodsX-ray diffraction
Resolution1.897 - 1.997 Å
Structure data

PDB-5ugn:
DNA polymerase beta imidodiphosphate reactant complex
Method: X-RAY DIFFRACTION / Resolution: 1.997 Å

PDB-5ugo:
DNA polymerase beta nick complex with imidodiphosphate
Method: X-RAY DIFFRACTION / Resolution: 1.897 Å

PDB-5ugp:
DNA polymerase beta complex with a 1nt gap and dCMPPNP
Method: X-RAY DIFFRACTION / Resolution: 1.955 Å

Chemicals

ChemComp-2PN:
IMIDODIPHOSPHORIC ACID

ChemComp-MG:
Unknown entry

ChemComp-8CP:
2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonoamino)phosphoryl]oxy}phosphoryl]cytidine

ChemComp-HOH:
WATER

ChemComp-CA:
Unknown entry

Source
  • homo sapiens (human)
  • synthetic construct (others)
KeywordsTransferase/DNA / transferase / lyase / dna domain / Transferase-DNA complex

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