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Structure paper

TitleStructural basis for IL-1 alpha recognition by a modified DNA aptamer that specifically inhibits IL-1 alpha signaling.
Journal, issue, pagesNat Commun, Vol. 8, Page 810-810, Year 2017
Publish dateDec 21, 2016 (structure data deposition date)
AuthorsRen, X. / Gelinas, A.D. / von Carlowitz, I. / Janjic, N. / Pyle, A.M.
External linksNat Commun / PubMed:28993621
MethodsX-ray diffraction
Resolution2.1 Å
Structure data

PDB-5uc6:
Structural insights into IL-1 alpha recognition by a naphthyl-modified aptamer that mimics IL-1RI Domain III
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-NA:
Unknown entry

ChemComp-PO4:
PHOSPHATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • synthetic construct (others)
KeywordsIMMUNE SYSTEM/DNA / SOMAmer / IMMUNE SYSTEM-DNA complex

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