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-Structure paper
Title | Design, Synthesis, and Properties of a Potent Inhibitor of Pseudomonas aeruginosa Deacetylase LpxC. |
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Journal, issue, pages | J. Med. Chem., Vol. 60, Page 5002-5014, Year 2017 |
Publish date | Dec 1, 2016 (structure data deposition date) |
![]() | Piizzi, G. / Parker, D.T. / Peng, Y. / Dobler, M. / Patnaik, A. / Wattanasin, S. / Liu, E. / Lenoir, F. / Nunez, J. / Kerrigan, J. ...Piizzi, G. / Parker, D.T. / Peng, Y. / Dobler, M. / Patnaik, A. / Wattanasin, S. / Liu, E. / Lenoir, F. / Nunez, J. / Kerrigan, J. / McKenney, D. / Osborne, C. / Yu, D. / Lanieri, L. / Bojkovic, J. / Dzink-Fox, J. / Lilly, M.D. / Sprague, E.R. / Lu, Y. / Wang, H. / Ranjitkar, S. / Xie, L. / Wang, B. / Glick, M. / Hamann, L.G. / Tommasi, R. / Yang, X. / Dean, C.R. |
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Methods | X-ray diffraction |
Resolution | 1.75 - 2 Å |
Structure data | ![]() PDB-5u39: ![]() PDB-5u3b: |
Chemicals | ![]() ChemComp-ZN: ![]() ChemComp-C90: ![]() ChemComp-HOH: ![]() ChemComp-7TD: ![]() ChemComp-EPE: |
Source |
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![]() | HYDROLASE / LPXC / HYDROXYMATE / GRAM NEGATIVE |