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TitleCrystal Structure of Mycobacterium tuberculosis Dihydrofolate Reductase Bound to NADP and p65 Inhibitor
Journal, issue, pagesTO BE PUBLISHED
Publish dateNov 29, 2016 (structure data deposition date)
AuthorsMayclin, S.J. / Fairman, J.W. / Lorimer, D.D. / Edwards, T.E.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.05 Å
Structure data

PDB-5u27:
Crystal Structure of Mycobacterium tuberculosis Dihydrofolate Reductase Bound to NADP and p65 Inhibitor
Method: X-RAY DIFFRACTION / Resolution: 2.05 Å

Chemicals

ChemComp-NAP:
NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-P65:
2,4-diamino-6-methyl-5-[3-(2,4,5-trichlorophenoxy)propyloxy]pyrimidine

ChemComp-HOH:
WATER

Source
  • mycobacterium tuberculosis (bacteria)
KeywordsOXIDOREDUCTASE / Folate / Structural Genomics / Seattle Structural Genomics Center for Infectious Disease / SSGCID

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