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Structure paper

TitleHigh-resolution crystal structure of the human CB1 cannabinoid receptor.
Journal, issue, pagesNature, Year 2016
Publish dateNov 23, 2016 (structure data deposition date)
AuthorsShao, Z. / Yin, J. / Chapman, K. / Grzemska, M. / Clark, L. / Wang, J. / Rosenbaum, D.M.
External linksNature / PubMed:27851727
MethodsX-ray diffraction
Resolution2.6 Å
Structure data

PDB-5u09:
High-resolution crystal structure of the human CB1 cannabinoid receptor
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

Chemicals

ChemComp-PEG:
DI(HYDROXYETHYL)ETHER

ChemComp-SO4:
SULFATE ION

ChemComp-7DY:
N-[(2S,3S)-4-(4-chlorophenyl)-3-(3-cyanophenyl)butan-2-yl]-2-methyl-2-{[5-(trifluoromethyl)pyridin-2-yl]oxy}propanamide / agonist*YM

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • pyrococcus abyssi (strain ge5 / orsay) (archaea)
KeywordsMEMBRANE PROTEIN / helix

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