EMDB/PDB/SASBDBから引用されている文献のデータベース

キーワード
構造解析手法	All X線回折 NMR 電子顕微鏡小角散乱中性子線回折線維回折粉末回折赤外分光 EPR FRET 理論モデルハイブリッド
著者・登録者
ジャーナル
IF	>30 >20 >10 >5 all

タイトル	Identification of a New Zinc Binding Chemotype by Fragment Screening.
ジャーナル・号・ページ	J. Med. Chem., Vol. 60, Page 7333-7349, Year 2017
掲載日	2016年11月17日 (構造データの登録日)
著者	Chrysanthopoulos, P.K. / Mujumdar, P. / Woods, L.A. / Dolezal, O. / Ren, B. / Peat, T.S. / Poulsen, S.A.
リンク	J. Med. Chem. / PubMed:28817930
手法	X線回折
解像度	1.206 - 1.6 Å
構造データ	PDB-5txy: Identification of a New Zinc Binding Chemotype of by Fragment Screening on human carbonic anhydrase 手法: X-RAY DIFFRACTION / 解像度: 1.206 Å PDB-5ty1: Identification of a New Zinc Binding Chemotype by Fragment Screening 手法: X-RAY DIFFRACTION / 解像度: 1.6 Å PDB-5ty8: Identification of a New Zinc Binding Chemotype by Fragment Screening 手法: X-RAY DIFFRACTION / 解像度: 1.45 Å PDB-5ty9: Identification of a New Zinc Binding Chemotype by Fragment Screening 手法: X-RAY DIFFRACTION / 解像度: 1.53 Å PDB-5tya: Identification of a New Zinc Binding Chemotype by Fragment Screening 手法: X-RAY DIFFRACTION / 解像度: 1.5 Å PDB-5u0d: Identification of a New Zinc Binding Chemotype by Fragment Screening 手法: X-RAY DIFFRACTION / 解像度: 1.59 Å PDB-5u0e: Identification of a New Zinc Binding Chemotype by Fragment Screening 手法: X-RAY DIFFRACTION / 解像度: 1.27 Å PDB-5u0f: Identification of a New Zinc Binding Chemotype by Fragment Screening 手法: X-RAY DIFFRACTION / 解像度: 1.21 Å PDB-5u0g: Identification of a New Zinc Binding Chemotype by Fragment Screening 手法: X-RAY DIFFRACTION / 解像度: 1.54 Å PDB-5vgy: Identification of a New Zinc Binding Chemotype by Fragment Screening 手法: X-RAY DIFFRACTION / 解像度: 1.39 Å
化合物	ChemComp-ZN: Unknown entry ChemComp-FMT: FORMIC ACID ChemComp-7Q1: (5R)-5-phenyl-1,3-oxazolidine-2,4-dione ChemComp-HOH: WATER ChemComp-7QV: (5R)-5-(2,4-dimethoxyphenyl)-1,3-oxazolidine-2,4-dione ChemComp-NA: Unknown entry ChemComp-7QS: (5R)-5-phenyl-1,3-thiazolidine-2,4-dione ChemComp-7R7: (5R)-5-(2,4-dimethoxyphenyl)-2-sulfanylidene-1,3-oxazolidin-4-one ChemComp-GOL: GLYCEROL ChemComp-7R4: (5R)-5-benzyl-2-sulfanylidene-1,3-thiazolidin-4-one ChemComp-EDO: 1,2-ETHANEDIOL ChemComp-7R1: (5R)-5-[(2,4-dimethoxyphenyl)methyl]-2-sulfanylidene-1,3-thiazolidin-4-one ChemComp-7QY: (5R)-5-[(2,4-dimethoxyphenyl)methyl]-1,3-thiazolidine-2,4-dione ChemComp-9AA: (5S)-5-[(2,4-dimethoxyphenyl)methyl]-5-hydroxy-2-sulfanylideneimidazolidin-4-one
由来	homo sapiens (ヒト)
キーワード	LYASE / human carbonic anhydrase / Zinc Binding Chemotype / crystal / crystallization / Fragment screening / carbonic anhydrase / LYASE/LYASE inhibitor / LYASE-LYASE inhibitor complex