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Title7-Carboxy-7-deazaguanine Synthase: A Radical S-Adenosyl-l-methionine Enzyme with Polar Tendencies.
Journal, issue, pagesJ. Am. Chem. Soc., Vol. 139, Page 1912-1920, Year 2017
Publish dateSep 28, 2016 (structure data deposition date)
AuthorsBruender, N.A. / Grell, T.A. / Dowling, D.P. / McCarty, R.M. / Drennan, C.L. / Bandarian, V.
External linksJ. Am. Chem. Soc. / PubMed:28045519
MethodsX-ray diffraction
Resolution2.407 - 2.548 Å
Structure data

PDB-5tgs:
Crystal Structure of QueE from Bacillus subtilis with methionine bound
Method: X-RAY DIFFRACTION / Resolution: 2.548 Å

PDB-5th5:
Crystal Structure of QueE from Bacillus subtilis with 6-carboxypterin-5'-deoxyadenosyl ester bound
Method: X-RAY DIFFRACTION / Resolution: 2.407 Å

Chemicals

ChemComp-SF4:
IRON/SULFUR CLUSTER

ChemComp-MET:
METHIONINE

ChemComp-PEG:
DI(HYDROXYETHYL)ETHER

ChemComp-HOH:
WATER

ChemComp-7C5:
5'-O-(2-amino-4-oxo-1,4-dihydropteridine-6-carbonyl)adenosine

Source
  • bacillus subtilis (bacteria)
KeywordsLYASE / S-Adenosylmethionine radical enzyme / 7-Carboxy-7-deazaguanine synthase

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