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-Structure paper
Title | Pomhex, a cell-permeable Enolase inhibitor for Collateral Lethality targeting of ENO1-deleted Glioblastoma |
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Journal, issue, pages | To Be Published |
Publish date | Feb 24, 2016 (structure data deposition date) |
Authors | Lin, Y.H. / Satani, N. / Hammoudi, N. / Felini, F. / Leonard, P.G. / Maxwell, D. / Peng, Z. / Link, T.M. / Lee, G.R. / Bosajou, A. ...Lin, Y.H. / Satani, N. / Hammoudi, N. / Felini, F. / Leonard, P.G. / Maxwell, D. / Peng, Z. / Link, T.M. / Lee, G.R. / Bosajou, A. / Sun, D. / Marszalek, J.R. / Sun, Y.T. / McMurray, J. / Mandal, P.J. / Zielinski, R. / Priebe, W. / DiFrancesco, M.E. / Czako, B. / Wang, Y.A. / Bornmann, W. / DePinho, R.A. / Muller, F.L. |
External links | Search PubMed |
Methods | X-ray diffraction |
Resolution | 2.318 - 2.63 Å |
Structure data | PDB-5idz: PDB-5td9: |
Chemicals | ChemComp-MG: ChemComp-6BM: ChemComp-PGE: ChemComp-HOH: ChemComp-CL: |
Source |
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Keywords | LYASE/LYASE INHIBITOR / enolase gamma / glycolysis / neuron specific enolase / carbohydrate metabolism / LYASE-LYASE INHIBITOR complex / LYASE |