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-Structure paper
Title | Synthesis and biological evaluation of novel selective androgen receptor modulators (SARMs). Part II: Optimization of 4-(pyrrolidin-1-yl)benzonitrile derivatives. |
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Journal, issue, pages | Bioorg. Med. Chem. Lett., Vol. 27, Page 1897-1901, Year 2017 |
Publish date | Sep 7, 2016 (structure data deposition date) |
![]() | Asano, M. / Hitaka, T. / Imada, T. / Yamada, M. / Morimoto, M. / Shinohara, H. / Hara, T. / Yamaoka, M. / Santou, T. / Nakayama, M. ...Asano, M. / Hitaka, T. / Imada, T. / Yamada, M. / Morimoto, M. / Shinohara, H. / Hara, T. / Yamaoka, M. / Santou, T. / Nakayama, M. / Imai, Y. / Habuka, N. / Yano, J. / Wilson, K. / Fujita, H. / Hasuoka, A. |
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Methods | X-ray diffraction |
Resolution | 2.7 - 2.71 Å |
Structure data | ![]() PDB-5t8e: ![]() PDB-5t8j: |
Chemicals | ![]() ChemComp-GOL: ![]() ChemComp-77U: ![]() ChemComp-HOH: ![]() ChemComp-77T: |
Source |
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![]() | HORMONE RECEPTOR / Androgen Receptor / selective androgen receptor modulators / SARMS |