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-Structure paper
Title | Tuning DNA binding affinity and cleavage specificity of an engineered gene-targeting nuclease via surface display, flow cytometry and cellular analyses. |
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Journal, issue, pages | Protein Eng. Des. Sel., Vol. 30, Page 503-522, Year 2017 |
Publish date | Sep 7, 2016 (structure data deposition date) |
![]() | Niyonzima, N. / Lambert, A.R. / Werther, R. / De Silva Feelixge, H. / Roychoudhury, P. / Greninger, A.L. / Stone, D. / Stoddard, B.L. / Jerome, K.R. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 2.15 - 2.4 Å |
Structure data | ![]() PDB-5t8d: ![]() PDB-5v0q: |
Chemicals | ![]() ChemComp-CA: ![]() ChemComp-HOH: |
Source |
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![]() | HYDROLASE/DNA / Meganuclease / Engineered protein / DNA complex / Homing Endonuclease / HYDROLASE-DNA complex |