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TitleNew imine-reducing enzymes from beta-hydroxyacid dehydrogenases by single amino acid substitutions.
Journal, issue, pagesProtein Eng. Des. Sel., Vol. 31, Page 109-120, Year 2018
Publish dateJul 3, 2017 (structure data deposition date)
AuthorsLenz, M. / Fademrecht, S. / Sharma, M. / Pleiss, J. / Grogan, G. / Nestl, B.M.
External linksProtein Eng. Des. Sel. / PubMed:29733377
MethodsX-ray diffraction
Resolution1.81 Å
Structure data

PDB-5ocm:
Imine Reductase from Streptosporangium roseum in complex with NADP+ and 2,2,2-trifluoroacetophenone hydrate
Method: X-RAY DIFFRACTION / Resolution: 1.81 Å

Chemicals

ChemComp-NAP:
NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE

ChemComp-9RH:
2,2,2-trifluoromethyl acetophenone hydrate

ChemComp-MG:
Unknown entry

ChemComp-HOH:
WATER

Source
  • streptosporangium roseum (bacteria)
KeywordsOXIDOREDUCTASE / Imine / Amine / NADPH

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