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Structure paper

TitleEffect of Noncanonical Amino Acids on Protein-Carbohydrate Interactions: Structure, Dynamics, and Carbohydrate Affinity of a Lectin Engineered with Fluorinated Tryptophan Analogs.
Journal, issue, pagesACS Chem. Biol., Vol. 13, Page 2211-2219, Year 2018
Publish dateJun 9, 2017 (structure data deposition date)
AuthorsTobola, F. / Lelimousin, M. / Varrot, A. / Gillon, E. / Darnhofer, B. / Blixt, O. / Birner-Gruenberger, R. / Imberty, A. / Wiltschi, B.
External linksACS Chem. Biol. / PubMed:29812892
MethodsX-ray diffraction
Resolution1.15 - 1.35 Å
Structure data

PDB-5o7u:
Crystal structure of the 7-Fluorotryptophan RSL lectin in complex with Lewis x tetrasaccharide
Method: X-RAY DIFFRACTION / Resolution: 1.15 Å

PDB-5o7v:
Crystal structure of the 5F-tryptophan RSL lectin in complex with Lewis x tetrasaccharide
Method: X-RAY DIFFRACTION / Resolution: 1.28 Å

PDB-5o7w:
Crystal structure of the 4-FLUORO RSL lectin in complex with Lewis x tetrasaccharide
Method: X-RAY DIFFRACTION / Resolution: 1.35 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-CA:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-EOH:
ETHANOL

ChemComp-CL:
Unknown entry

ChemComp-NA:
Unknown entry

ChemComp-EDO:
1,2-ETHANEDIOL

Source
  • ralstonia solanacearum (bacteria)
KeywordsSUGAR BINDING PROTEIN / lectin / fluorinated tryptophan / lewis X / CARBOHYDRATE

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