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-Structure paper
Title | A potent, proteolysis-resistant inhibitor of kallikrein-related peptidase 6 (KLK6) for cancer therapy, developed by combinatorial engineering. |
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Journal, issue, pages | J. Biol. Chem., Vol. 293, Page 12663-12680, Year 2018 |
Publish date | May 9, 2017 (structure data deposition date) |
![]() | Sananes, A. / Cohen, I. / Shahar, A. / Hockla, A. / De Vita, E. / Miller, A.K. / Radisky, E.S. / Papo, N. |
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Methods | X-ray diffraction |
Resolution | 1.853 - 2.296 Å |
Structure data | ![]() PDB-5nx1: ![]() PDB-5nx3: |
Chemicals | ![]() ChemComp-HOH: |
Source |
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![]() | HYDROLASE / Serine_protease / inhibitor / complex / Hydrolase-Inhibitor complex |