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-Structure paper
| Title | Molecular basis of USP7 inhibition by selective small-molecule inhibitors. |
|---|---|
| Journal, issue, pages | Nature, Vol. 550, Page 481-486, Year 2017 |
| Publish date | Mar 17, 2017 (structure data deposition date) |
 Authors | Turnbull, A.P. / Ioannidis, S. / Krajewski, W.W. / Pinto-Fernandez, A. / Heride, C. / Martin, A.C.L. / Tonkin, L.M. / Townsend, E.C. / Buker, S.M. / Lancia, D.R. ...Turnbull, A.P. / Ioannidis, S. / Krajewski, W.W. / Pinto-Fernandez, A. / Heride, C. / Martin, A.C.L. / Tonkin, L.M. / Townsend, E.C. / Buker, S.M. / Lancia, D.R. / Caravella, J.A. / Toms, A.V. / Charlton, T.M. / Lahdenranta, J. / Wilker, E. / Follows, B.C. / Evans, N.J. / Stead, L. / Alli, C. / Zarayskiy, V.V. / Talbot, A.C. / Buckmelter, A.J. / Wang, M. / McKinnon, C.L. / Saab, F. / McGouran, J.F. / Century, H. / Gersch, M. / Pittman, M.S. / Marshall, C.G. / Raynham, T.M. / Simcox, M. / Stewart, L.M.D. / McLoughlin, S.B. / Escobedo, J.A. / Bair, K.W. / Dinsmore, C.J. / Hammonds, T.R. / Kim, S. / Urbe, S. / Clague, M.J. / Kessler, B.M. / Komander, D. |
 External links | Nature / PubMed:29045389 |
| Methods | X-ray diffraction |
| Resolution | 2.33 - 2.35 Å |
| Structure data |  PDB-5nge:  PDB-5ngf: |
| Chemicals |  ChemComp-8WK:  ChemComp-HOH:  ChemComp-8WN:  ChemComp-EDO: |
| Source |
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 Keywords | HYDROLASE / DEUBIQUITINATION |
homo sapiens (human)