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-Structure paper
Title | Structural insights into the enzymatic activity and potential substrate promiscuity of human 3-phosphoglycerate dehydrogenase (PHGDH). |
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Journal, issue, pages | Oncotarget, Vol. 8, Page 104478-104491, Year 2017 |
Publish date | Feb 14, 2017 (structure data deposition date) |
Authors | Unterlass, J.E. / Wood, R.J. / Basle, A. / Tucker, J. / Cano, C. / Noble, M.M.E. / Curtin, N.J. |
External links | Oncotarget / PubMed:29262655 |
Methods | X-ray diffraction |
Resolution | 2.3 Å |
Structure data | PDB-5n6c: |
Chemicals | ChemComp-TLA: ChemComp-NAD: ChemComp-HOH: |
Source |
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Keywords | OXIDOREDUCTASE / dehydrogenase / serine metabolism / enzymology |