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Title | Structural insights unravel the zymogenic mechanism of the virulence factor gingipain K from Porphyromonas gingivalis, a causative agent of gum disease from the human oral microbiome. |
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Journal, issue, pages | J. Biol. Chem., Vol. 292, Page 5724-5735, Year 2017 |
Publish date | Jan 13, 2017 (structure data deposition date) |
Authors | Pomowski, A. / Uson, I. / Nowakowska, Z. / Veillard, F. / Sztukowska, M.N. / Guevara, T. / Goulas, T. / Mizgalska, D. / Nowak, M. / Potempa, B. ...Pomowski, A. / Uson, I. / Nowakowska, Z. / Veillard, F. / Sztukowska, M.N. / Guevara, T. / Goulas, T. / Mizgalska, D. / Nowak, M. / Potempa, B. / Huntington, J.A. / Potempa, J. / Gomis-Ruth, F.X. |
External links | J. Biol. Chem. / PubMed:28196869 |
Methods | X-ray diffraction |
Resolution | 1.8 Å |
Structure data | PDB-5mun: |
Chemicals | ChemComp-AZI: ChemComp-HOH: |
Source |
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Keywords | HYDROLASE / Cysteine protease / zymogenic latency |