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Title | Targeting Endoplasmic Reticulum alpha-Glucosidase I with a Single-Dose Iminosugar Treatment Protects against Lethal Influenza and Dengue Virus Infections. |
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Journal, issue, pages | J. Med. Chem., Year 2020 |
Publish date | Nov 24, 2016 (structure data deposition date) |
![]() | Warfield, K.L. / Alonzi, D.S. / Hill, J.C. / Caputo, A.T. / Roversi, P. / Kiappes, J.L. / Sheets, N. / Duchars, M. / Dwek, R.A. / Biggins, J. ...Warfield, K.L. / Alonzi, D.S. / Hill, J.C. / Caputo, A.T. / Roversi, P. / Kiappes, J.L. / Sheets, N. / Duchars, M. / Dwek, R.A. / Biggins, J. / Barnard, D. / Shresta, S. / Treston, A.M. / Zitzmann, N. |
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Methods | X-ray diffraction |
Resolution | 2.1 Å |
Structure data | ![]() PDB-5mhf: |
Chemicals | ![]() ChemComp-SO4: ![]() ChemComp-6A9: ![]() ChemComp-7PG: ![]() ChemComp-HOH: |
Source |
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![]() | HYDROLASE / GH63 / Glucosidase / Iminosugar |