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Structure paper

TitleTranslation initiation factor 4E in complex with (SP)-m2(7,2'O)GppSpA mRNA 5' cap analog
Journal, issue, pagesTo Be Published
Publish dateOct 28, 2016 (structure data deposition date)
AuthorsWarminski, M. / Nowak, E. / Kubacka, D. / Kowalska, J. / Nowotny, M. / Jemielity, J.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.85 Å
Structure data

PDB-5m84:
Translation initiation factor 4E in complex with (SP)-m2(7,2'O)GppSpA mRNA 5' cap analog
Method: X-RAY DIFFRACTION / Resolution: 1.85 Å

Chemicals

ChemComp-YDZ:
[[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-sulfanyl-phosphoryl] [(2~{R},3~{R},4~{R},5~{R})-5-(2-azanyl-7-methyl-6-oxidanyl-purin-7-ium-9-yl)-4-methoxy-3-oxidanyl-oxolan-2-yl]methyl hydrogen phosphate

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
KeywordsRNA BINDING PROTEIN / Protein-ligand complex / translation initiation factor / eIF4E / m2(7 / 2'O)GppSpA / phosphorothioate / mRNA 5' cap analog / translation

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