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-Structure paper
Title | Structure-Activity Relationships of Small Molecule Autotaxin Inhibitors with a Discrete Binding Mode. |
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Journal, issue, pages | J. Med. Chem., Vol. 60, Page 722-748, Year 2017 |
Publish date | Aug 17, 2016 (structure data deposition date) |
![]() | Miller, L.M. / Keune, W.J. / Castagna, D. / Young, L.C. / Duffy, E.L. / Potjewyd, F. / Salgado-Polo, F. / Engel Garcia, P. / Semaan, D. / Pritchard, J.M. ...Miller, L.M. / Keune, W.J. / Castagna, D. / Young, L.C. / Duffy, E.L. / Potjewyd, F. / Salgado-Polo, F. / Engel Garcia, P. / Semaan, D. / Pritchard, J.M. / Perrakis, A. / Macdonald, S.J. / Jamieson, C. / Watson, A.J. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 2.4 Å |
Structure data | ![]() PDB-5lqq: |
Chemicals | ![]() ChemComp-ZN: ![]() ChemComp-CA: ![]() ChemComp-IOD: ![]() ChemComp-72P: ![]() ChemComp-NA: ![]() ChemComp-HOH: |
Source |
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![]() | HYDROLASE / Autotaxin / ENPP2 / Inhibitor / LM350 / Ectonucleotide pyrophosphatase/phosphodiesterase |