+Search query
-Structure paper
Title | Structure guided design of a series of selective pyrrolopyrimidinone MARK inhibitors. |
---|---|
Journal, issue, pages | Bioorg. Med. Chem. Lett., Vol. 27, Page 114-120, Year 2017 |
Publish date | Jul 23, 2016 (structure data deposition date) |
![]() | Katz, J.D. / Haidle, A. / Childers, K.K. / Zabierek, A.A. / Jewell, J.P. / Hou, Y. / Altman, M.D. / Szewczak, A. / Chen, D. / Harsch, A. ...Katz, J.D. / Haidle, A. / Childers, K.K. / Zabierek, A.A. / Jewell, J.P. / Hou, Y. / Altman, M.D. / Szewczak, A. / Chen, D. / Harsch, A. / Hayashi, M. / Warren, L. / Hutton, M. / Nuthall, H. / Su, H.P. / Munshi, S. / Stanton, M.G. / Davies, I.W. / Munoz, B. / Northrup, A. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 3.2 - 3.21 Å |
Structure data | ![]() PDB-5kz7: ![]() PDB-5kz8: |
Chemicals | ![]() ChemComp-6Z2: ![]() ChemComp-6Z5: |
Source |
|
![]() | Transferase/Transferase Inhibitor / Mark / Serine/threonine-protein kinase / Transferase-Transferase Inhibitor complex |