+Search query
-Structure paper
Title | Effects of Hinge-region Natural Polymorphisms on Human Immunodeficiency Virus-Type 1 Protease Structure, Dynamics, and Drug Pressure Evolution. |
---|---|
Journal, issue, pages | J. Biol. Chem., Vol. 291, Page 22741-22756, Year 2016 |
Publish date | Jul 6, 2016 (structure data deposition date) |
Authors | Liu, Z. / Huang, X. / Hu, L. / Pham, L. / Poole, K.M. / Tang, Y. / Mahon, B.P. / Tang, W. / Li, K. / Goldfarb, N.E. ...Liu, Z. / Huang, X. / Hu, L. / Pham, L. / Poole, K.M. / Tang, Y. / Mahon, B.P. / Tang, W. / Li, K. / Goldfarb, N.E. / Dunn, B.M. / McKenna, R. / Fanucci, G.E. |
External links | J. Biol. Chem. / PubMed:27576689 |
Methods | X-ray diffraction |
Resolution | 1.6 - 2.4 Å |
Structure data | PDB-5kqx: PDB-5kqy: PDB-5kqz: PDB-5kr0: PDB-5kr1: PDB-5kr2: |
Chemicals | ChemComp-ROC: ChemComp-HOH: ChemComp-017: ChemComp-0Q4: ChemComp-478: ChemComp-GOL: |
Source |
|
Keywords | HYDROLASE/HUDROLASE INHIBITOR / HIV-1 protease / E35D / salt-bridge interaction / Natural polymorphism / HYDROLASE-HUDROLASE INHIBITOR complex / HYDROLASE/HYDROLASE INHIBITOR / HYDROLASE-HYDROLASE INHIBITOR complex / HYDROLASE |