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TitleStructure of neprilysin in complex with the active metabolite of sacubitril.
Journal, issue, pagesSci Rep, Vol. 6, Page 27909-27909, Year 2016
Publish dateApr 29, 2016 (structure data deposition date)
AuthorsSchiering, N. / D'Arcy, A. / Villard, F. / Ramage, P. / Logel, C. / Cumin, F. / Ksander, G.M. / Wiesmann, C. / Karki, R.G. / Mogi, M.
External linksSci Rep / PubMed:27302413
MethodsX-ray diffraction
Resolution2 Å
Structure data

PDB-5jmy:
NEPRILYSIN COMPLEXED WITH LBQ657
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-ZN:
Unknown entry

ChemComp-6LD:
Sacubitrilat

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHYDROLASE / LBQ657 / sacubitril / heart failure

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