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TitleInhibition of Mycobacterium tuberculosis dihydrodipicolinate synthase by alpha-ketopimelic acid and its other structural analogues
Journal, issue, pagesSci Rep, Vol. 6, Page 30827-30827, Year 2016
Publish dateApr 2, 2016 (structure data deposition date)
AuthorsShrivastava, P. / Navratna, V. / Silla, Y. / Dewangan, R.P. / Pramanik, A. / Chaudhary, S. / Rayasam, G. / Kumar, A. / Gopal, B. / Ramachandran, S.
External linksSci Rep / PubMed:27501775
MethodsX-ray diffraction
Resolution2.4 Å
Structure data

PDB-5j5d:
Crystal structure of Dihydrodipicolinate Synthase from Mycobacterium tuberculosis in complex with alpha-ketopimelic acid
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

Chemicals

ChemComp-NA:
Unknown entry

ChemComp-6GT:
2-oxoheptanedioic acid

ChemComp-HOH:
WATER

Source
  • mycobacterium tuberculosis h37rv (bacteria)
KeywordsLYASE / Dap pathway / L-lysine / alpha-ketopimelic acid

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