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TitleDistortion of the ligand molecule as a strategy for modulating binding affinity: Further studies involving complexes of jacalin with beta-substituted disaccharides.
Journal, issue, pagesIUBMB Life, Vol. 69, Page 72-78, Year 2017
Publish dateApr 1, 2016 (structure data deposition date)
AuthorsAbhinav, K.V. / Sharma, K. / Surolia, A. / Vijayan, M.
External linksIUBMB Life / PubMed:28111895
MethodsX-ray diffraction
Resolution1.65 - 1.94 Å
Structure data

PDB-5j4t:
Structure of tetrameric jacalin complexed with GlcNAc beta-(1,3) Gal-beta-OMe
Method: X-RAY DIFFRACTION / Resolution: 1.94 Å

PDB-5j4x:
Structure of tetrameric jacalin complexed with Gal beta-(1,3) Gal-beta-OMe
Method: X-RAY DIFFRACTION / Resolution: 1.65 Å

Chemicals

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-PEG:
DI(HYDROXYETHYL)ETHER

ChemComp-MBG:
methyl beta-D-galactopyranoside

ChemComp-HOH:
WATER

ChemComp-IPA:
ISOPROPYL ALCOHOL / alkaloid*YM

Source
  • artocarpus integer (campedak)
KeywordsSUGAR BINDING PROTEIN / Plant lectins / Galactose specific lectin / beta-prism I fold / post translational proteolysis / T-antigen binding protein / reducing and non-reducing sugars / Plant lectins and sugar binding protein

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