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-Structure paper
Title | A Small Covalent Allosteric Inhibitor of Human Cytomegalovirus DNA Polymerase Subunit Interactions. |
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Journal, issue, pages | ACS Infect Dis, Vol. 3, Page 112-118, Year 2017 |
Publish date | Mar 22, 2016 (structure data deposition date) |
![]() | Chen, H. / Coseno, M. / Ficarro, S.B. / Mansueto, M.S. / Komazin-Meredith, G. / Boissel, S. / Filman, D.J. / Marto, J.A. / Hogle, J.M. / Coen, D.M. |
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Methods | X-ray diffraction |
Resolution | 2.56 - 2.684 Å |
Structure data | ![]() PDB-5iwd: ![]() PDB-5ixa: |
Chemicals | ![]() ChemComp-6EV: ![]() ChemComp-HOH: |
Source |
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![]() | REPLICATION/REPLICATION INHIBITOR / covalent inhibitor / HCMV Pol accessory subunit / protein-protein interaction / human cytomegalovirus / DNA polymerase / processivity factor / REPLICATION-REPLICATION INHIBITOR complex / REPLICATION |