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-Structure paper
Title | An integrated model of RAF inhibitor action predicts inhibitor activity against oncogenic BRAF signaling |
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Journal, issue, pages | Cancer Cell, Vol. 30, Page 1-14, Year 2016 |
Publish date | Dec 24, 2014 (structure data deposition date) |
![]() | Karoulia, Z. / Wu, Y. / Ahmed, T.A. / Qisheng, X. / Bollard, J. / Krepler, C. / Wu, X. / Zhang, C. / Bollag, G. / Herlym, M. ...Karoulia, Z. / Wu, Y. / Ahmed, T.A. / Qisheng, X. / Bollard, J. / Krepler, C. / Wu, X. / Zhang, C. / Bollag, G. / Herlym, M. / Fagin, J.A. / Lujambio, A. / Gavathiotis, E. / Poulikakos, P.I. |
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Methods | X-ray diffraction |
Resolution | 1.95 - 3.493 Å |
Structure data | ![]() PDB-4rzv: ![]() PDB-4rzw: ![]() PDB-5ita: |
Chemicals | ![]() ChemComp-032: ![]() ChemComp-B1E: ![]() ChemComp-6DC: ![]() ChemComp-HOH: |
Source |
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![]() | Transferase/Transferase Inhibitor / Transferase-Transferase Inhibitor complex / transferase / kinase and inhibitor complex |