+Search query
-Structure paper
Title | Design and synthesis of novel 3-sulfonylpyrazol-4-amino pyrimidines as potent anaplastic lymphoma kinase (ALK) inhibitors. |
---|---|
Journal, issue, pages | Bioorg. Med. Chem. Lett., Vol. 26, Page 1910-1918, Year 2016 |
Publish date | Mar 7, 2016 (structure data deposition date) |
Authors | Zhang, P. / Dong, J. / Zhong, B. / Zhang, D. / Yuan, H. / Jin, C. / Xu, X. / Li, H. / Zhou, Y. / Liang, Z. ...Zhang, P. / Dong, J. / Zhong, B. / Zhang, D. / Yuan, H. / Jin, C. / Xu, X. / Li, H. / Zhou, Y. / Liang, Z. / Ji, M. / Xu, T. / Song, G. / Zhang, L. / Chen, G. / Meng, X. / Sun, D. / Shih, J. / Zhang, R. / Hou, G. / Wang, C. / Jin, Y. / Yang, Q. |
External links | Bioorg. Med. Chem. Lett. / PubMed:26979157 |
Methods | X-ray diffraction |
Resolution | 2.12 Å |
Structure data | PDB-5imx: |
Chemicals | ChemComp-CZ4: ChemComp-HOH: |
Source |
|
Keywords | TRANSFERASE/TRANSFERASE INHIBITOR / Kinase / inhibitor / TRANSFERASE-TRANSFERASE INHIBITOR complex |