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-Structure paper
Title | Uncoupling JAK2 V617F activation from cytokine-induced signalling by modulation of JH2 alpha C helix. |
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Journal, issue, pages | Biochem. J., Vol. 473, Page 1579-1591, Year 2016 |
Publish date | Feb 12, 2016 (structure data deposition date) |
Authors | Leroy, E. / Dusa, A. / Colau, D. / Motamedi, A. / Cahu, X. / Mouton, C. / Huang, L.J. / Shiau, A.K. / Constantinescu, S.N. |
External links | Biochem. J. / PubMed:27029346 |
Methods | X-ray diffraction |
Resolution | 1.54 Å |
Structure data | PDB-5i4n: |
Chemicals | ChemComp-ATP: ChemComp-MG: ChemComp-GOL: ChemComp-HOH: |
Source |
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Keywords | TRANSFERASE / PSEUDOKINASE / ATP BINDING |