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TitleThe discovery and the structural basis of an imidazo[4,5-b]pyridine-based p21-activated kinase 4 inhibitor
Journal, issue, pagesBioorg. Med. Chem. Lett., Vol. 26, Page 2580-2583, Year 2016
Publish dateFeb 3, 2016 (structure data deposition date)
AuthorsPark, J.K. / Kim, S. / Han, Y.J. / Kim, S.H. / Kang, N.S. / Lee, H. / Park, S.Y.
External linksBioorg. Med. Chem. Lett. / PubMed:27117431
MethodsX-ray diffraction
Resolution3.09 Å
Structure data

PDB-5i0b:
Structure of PAK4
Method: X-RAY DIFFRACTION / Resolution: 3.09 Å

Chemicals

ChemComp-67U:
6-bromo-2-[1-methyl-3-(propan-2-yl)-1H-pyrazol-4-yl]-1H-imidazo[4,5-b]pyridine

Source
  • homo sapiens (human)
KeywordsTRANSFERASE/TRANSFERASE INIHIBITOR / kinase / TRANSFERASE-TRANSFERASE INIHIBITOR complex

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