+Search query
-Structure paper
Title | DNA-Encoded Library Screening Identifies Benzo[b][1,4]oxazepin-4-ones as Highly Potent and Monoselective Receptor Interacting Protein 1 Kinase Inhibitors. |
---|---|
Journal, issue, pages | J. Med. Chem., Vol. 59, Page 2163-2178, Year 2016 |
Publish date | Jan 29, 2016 (structure data deposition date) |
![]() | Harris, P.A. / King, B.W. / Bandyopadhyay, D. / Berger, S.B. / Campobasso, N. / Capriotti, C.A. / Cox, J.A. / Dare, L. / Dong, X. / Finger, J.N. ...Harris, P.A. / King, B.W. / Bandyopadhyay, D. / Berger, S.B. / Campobasso, N. / Capriotti, C.A. / Cox, J.A. / Dare, L. / Dong, X. / Finger, J.N. / Grady, L.C. / Hoffman, S.J. / Jeong, J.U. / Kang, J. / Kasparcova, V. / Lakdawala, A.S. / Lehr, R. / McNulty, D.E. / Nagilla, R. / Ouellette, M.T. / Pao, C.S. / Rendina, A.R. / Schaeffer, M.C. / Summerfield, J.D. / Swift, B.A. / Totoritis, R.D. / Ward, P. / Zhang, A. / Zhang, D. / Marquis, R.W. / Bertin, J. / Gough, P.J. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 2.23 Å |
Structure data | ![]() PDB-5hx6: |
Chemicals | ![]() ChemComp-65U: ![]() ChemComp-HOH: |
Source |
|
![]() | TRANSFERASE/TRANSFERASE INHIBITOR / Kinase / inhibitor complex / non-hinge binding / TRANSFERASE-TRANSFERASE INHIBITOR complex |