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TitleCrystal structure of human dihydroorotate dehydrogenase (DHODH) with 18L at 1.60 A resolution
Journal, issue, pagesTo Be Published
Publish dateJan 12, 2016 (structure data deposition date)
AuthorsHuang, J. / Wu, D. / Lu, Q. / Yao, X.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.6 Å
Structure data

PDB-5hin:
Crystal structure of human dihydroorotate dehydrogenase (DHODH) with 18L compound
Method: X-RAY DIFFRACTION / Resolution: 1.6 Å

Chemicals

ChemComp-FMN:
FLAVIN MONONUCLEOTIDE

ChemComp-ORO:
OROTIC ACID

ChemComp-SO4:
SULFATE ION

ChemComp-1KL:
methyl (2Z)-(3-{4-[(4-tert-butylphenyl)carbamoyl]phenyl}-4-oxo-1,3-thiazolidin-2-ylidene)(cyano)acetate

ChemComp-ACT:
ACETATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsOXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR / Inhibitor / OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR complex

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