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-Structure paper
Title | Discovery of trypanocidal coumarins with dual inhibition of both the glycerol kinase and alternative oxidase ofTrypanosoma brucei brucei. |
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Journal, issue, pages | Faseb J., Vol. 33, Page 13002-13013, Year 2019 |
Publish date | Jul 19, 2016 (structure data deposition date) |
![]() | Balogun, E.O. / Inaoka, D.K. / Shiba, T. / Tsuge, C. / May, B. / Sato, T. / Kido, Y. / Nara, T. / Aoki, T. / Honma, T. ...Balogun, E.O. / Inaoka, D.K. / Shiba, T. / Tsuge, C. / May, B. / Sato, T. / Kido, Y. / Nara, T. / Aoki, T. / Honma, T. / Tanaka, A. / Inoue, M. / Matsuoka, S. / Michels, P.A.M. / Watanabe, Y.I. / Moore, A.L. / Harada, S. / Kita, K. |
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Methods | X-ray diffraction |
Resolution | 2.5 - 3.2 Å |
Structure data | ![]() PDB-5gn5: ![]() PDB-5gn6: ![]() PDB-5gn7: ![]() PDB-5gn9: |
Chemicals | ![]() ChemComp-6XZ: ![]() ChemComp-GOL: ![]() ChemComp-HOH: ![]() ChemComp-6Y0: ![]() ChemComp-FE: ![]() ChemComp-OH: |
Source |
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![]() | TRANSFERASE / Glycerol kinase / inhibitor / drug / African trypanosomes / Alternative oxidase / OXIDO-REDUCTASE / OXIDOREDUCTASE |