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Structure paper

TitleStructure of the Dual-Mode Wnt Regulator Kremen1 and Insight Into Ternary Complex Formation with Lrp6 and Dickkopf
Journal, issue, pagesStructure, Vol. 24, Page 1599-, Year 2016
Publish dateFeb 21, 2016 (structure data deposition date)
AuthorsZebisch, M. / Jackson, V.A. / Zhao, Y. / Jones, E.Y.
External linksStructure / PubMed:27524201
MethodsX-ray diffraction
Resolution1.9 - 3.5 Å
Structure data

PDB-5fws:
Wnt modulator Kremen crystal form I at 1.90A
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

PDB-5fwt:
Wnt modulator Kremen crystal form I at 2.10A
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

PDB-5fwu:
Wnt modulator Kremen crystal form II at 2.8A
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

PDB-5fwv:
Wnt modulator Kremen crystal form III at 3.2A
Method: X-RAY DIFFRACTION / Resolution: 3.2 Å

PDB-5fww:
Wnt modulator Kremen in complex with DKK1 (CRD2) and LRP6 (PE3PE4)
Method: X-RAY DIFFRACTION / Resolution: 3.5 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-CA:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-PO4:
PHOSPHATE ION

ChemComp-CL:
Unknown entry

Source
  • homo sapiens (human)
KeywordsSIGNALING PROTEIN / WNT / CELL SURFACE / SIGNALLING / MEMBRANE PROTEIN

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