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TitleNon-Linear and Flexible Regions of the Human Notch1 Extracellular Domain Revealed by High-Resolution Structural Studies.
Journal, issue, pagesStructure, Vol. 24, Page 555-, Year 2016
Publish dateNov 2, 2015 (structure data deposition date)
AuthorsWeisshuhn, P.C. / Sheppard, D. / Taylor, P. / Whiteman, P. / Lea, S.M. / Handford, P.A. / Redfield, C.
External linksStructure / PubMed:26996961
MethodsX-ray diffraction
Resolution2.46 - 2.92 Å
Structure data

PDB-5fm9:
human Notch 1, EGF 4-7
Method: X-RAY DIFFRACTION / Resolution: 2.92 Å

PDB-5fma:
human Notch 1, EGF 4-7
Method: X-RAY DIFFRACTION / Resolution: 2.46 Å

Chemicals

ChemComp-CA:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-CL:
Unknown entry

ChemComp-EDO:
1,2-ETHANEDIOL

Source
  • homo sapiens (human)
KeywordsTRANSCRIPTION / TRANSMEMBRANE / DEVELOPMENTAL / PROTEIN / NOTCH SIGNALING PATHWAY / DIFFERENTIATION / PHOSPHORYLATION / EGF- LIKE DOMAIN / REGULATION / RECEPTOR / ACTIVATOR / ANK REPEAT / SIGNALLING / GLYCOPROTEIN / EXTRACELLULAR / EGF / NOTCH / JAGGED / MEMBRANE

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