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Structure paper

TitleCrystal structure of the bromodomain of human BRPF1 in complex with PFI-4 chemical probe
Journal, issue, pagesTo Be Published
Publish dateDec 20, 2015 (structure data deposition date)
AuthorsTallant, C. / Owen, D.R. / Gerstenberger, B.S. / Savitsky, P. / Chaikuad, A. / Fedorov, O. / Nunez-Alonso, G. / Filippakopoulos, P. / von Delft, F. / Arrowsmith, C.H. ...Tallant, C. / Owen, D.R. / Gerstenberger, B.S. / Savitsky, P. / Chaikuad, A. / Fedorov, O. / Nunez-Alonso, G. / Filippakopoulos, P. / von Delft, F. / Arrowsmith, C.H. / Edwards, A.M. / Brennan, P.E. / Bountra, C. / Muller, S. / Knapp, S.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.5 Å
Structure data

PDB-5fg5:
Crystal structure of the bromodomain of human BRPF1 in complex with PFI-4 chemical probe
Method: X-RAY DIFFRACTION / Resolution: 1.5 Å

Chemicals

ChemComp-5XF:
~{N}-(1,3-dimethyl-2-oxidanylidene-6-pyrrolidin-1-yl-benzimidazol-5-yl)-2-methoxy-benzamide

ChemComp-NO3:
NITRATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSCRIPTION / Peregrin / MOZ-MORF complex

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