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Structure paper

TitleStructural basis of cohesin cleavage by separase.
Journal, issue, pagesNature, Vol. 532, Page 131-134, Year 2016
Publish dateDec 14, 2015 (structure data deposition date)
AuthorsLin, Z. / Luo, X. / Yu, H.
External linksNature / PubMed:27027290
MethodsX-ray diffraction
Resolution1.84 - 3.1 Å
Structure data

PDB-5fby:
Crystal structure of ctSPD
Method: X-RAY DIFFRACTION / Resolution: 1.898 Å

PDB-5fc2:
Structure of a separase in complex with a pAMK peptide containing a phospho-serine
Method: X-RAY DIFFRACTION / Resolution: 1.84 Å

PDB-5fc3:
Structural basis of cohesin cleavage by separase
Method: X-RAY DIFFRACTION / Resolution: 3.1 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • chaetomium thermophilum (strain dsm 1495 / cbs 144.50 / imi 039719) (fungus)
  • synthetic construct (others)
  • chaetomium thermophilum (fungus)
KeywordsHYDROLASE / cohesin / complex / hydrolase/hydrolase inhibitor / hydrolase-hydrolase inhibitor complex / cysteine protease

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