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TitleScreening of saponins and sapogenins from Medicago species as potential PPAR gamma agonists and X-ray structure of the complex PPAR gamma /caulophyllogenin.
Journal, issue, pagesSci Rep, Vol. 6, Page 27658-27658, Year 2016
Publish dateDec 9, 2015 (structure data deposition date)
AuthorsMontanari, R. / Capelli, D. / Tava, A. / Galli, A. / Laghezza, A. / Tortorella, P. / Loiodice, F. / Pochetti, G.
External linksSci Rep / PubMed:27283034
MethodsX-ray diffraction
Resolution2.25 Å
Structure data

PDB-5f9b:
X-ray crystal structure of PPARgamma in the complex with caulophyllogenin
Method: X-RAY DIFFRACTION / Resolution: 2.25 Å

Chemicals

ChemComp-5VN:
Caulophyllogenin

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSCRIPTION / nuclear receptor / transcription factor / diabetes / bundle of alpha-helices

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