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Structure paper

TitleCrystal structure of FTO-CHTB
Journal, issue, pagesTo Be Published
Publish dateDec 9, 2015 (structure data deposition date)
AuthorsChai, J. / Zhou, B. / Liu, W. / Han, Z.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.2 Å
Structure data

PDB-5f8p:
A Novel Inhibitor of the Obesity-Related Protein FTO
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-FIJ:
4-chloranyl-6-[(2~{S})-6-chloranyl-2,4,4-trimethyl-7-oxidanyl-3~{H}-chromen-2-yl]benzene-1,3-diol

ChemComp-AKG:
2-OXOGLUTARIC ACID

ChemComp-FE2:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsOXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR / Fat mass and obesity associated(FTO) protein / small molecule / OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR complex

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