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-Structure paper
Title | Antivirulence Isoquinolone Mannosides: Optimization of the Biaryl Aglycone for FimH Lectin Binding Affinity and Efficacy in the Treatment of Chronic UTI. |
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Journal, issue, pages | Chemmedchem, Vol. 11, Page 367-373, Year 2016 |
Publish date | Dec 1, 2015 (structure data deposition date) |
Authors | Jarvis, C. / Han, Z. / Kalas, V. / Klein, R. / Pinkner, J.S. / Ford, B. / Binkley, J. / Cusumano, C.K. / Cusumano, Z. / Mydock-McGrane, L. ...Jarvis, C. / Han, Z. / Kalas, V. / Klein, R. / Pinkner, J.S. / Ford, B. / Binkley, J. / Cusumano, C.K. / Cusumano, Z. / Mydock-McGrane, L. / Hultgren, S.J. / Janetka, J.W. |
External links | Chemmedchem / PubMed:26812660 |
Methods | X-ray diffraction |
Resolution | 1.665 Å |
Structure data | PDB-5f2f: |
Chemicals | ChemComp-5U7: ChemComp-GOL: ChemComp-HOH: |
Source |
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Keywords | SUGAR BINDING PROTEIN / lectin / mannoside / immunoglobulin fold / carbohydrate binding protein |