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Structure paper

TitleSmall-Molecule Stabilization of the 14-3-3/Gab2 Protein-Protein Interaction (PPI) Interface.
Journal, issue, pagesChemmedchem, Vol. 11, Page 911-918, Year 2016
Publish dateNov 23, 2015 (structure data deposition date)
AuthorsBier, D. / Bartel, M. / Sies, K. / Halbach, S. / Higuchi, Y. / Haranosono, Y. / Brummer, T. / Kato, N. / Ottmann, C.
External linksChemmedchem / PubMed:26644359
MethodsX-ray diffraction
Resolution1.95 - 2.34 Å
Structure data

PDB-5ewz:
Small-molecule stabilization of the 14-3-3/Gab2 PPI interface
Method: X-RAY DIFFRACTION / Resolution: 2.34 Å

PDB-5exa:
Small-molecule stabilization of the 14-3-3/Gab2 PPI interface
Method: X-RAY DIFFRACTION / Resolution: 1.95 Å

Chemicals

ChemComp-BEZ:
BENZOIC ACID

ChemComp-HOH:
WATER

ChemComp-5SO:
Fusicoccin A-THF derivative

ChemComp-MG:
Unknown entry

Source
  • homo sapiens (human)
KeywordsSIGNALING PROTEIN / 14-3-3 / GAB2 / Protein / Diphosphorylation

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