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-Structure paper
Title | Novel Small Molecule Inhibitors of Choline Kinase Identified by Fragment-Based Drug Discovery. |
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Journal, issue, pages | J. Med. Chem., Vol. 59, Page 671-686, Year 2016 |
Publish date | Nov 12, 2015 (structure data deposition date) |
![]() | Zech, S.G. / Kohlmann, A. / Zhou, T. / Li, F. / Squillace, R.M. / Parillon, L.E. / Greenfield, M.T. / Miller, D.P. / Qi, J. / Thomas, R.M. ...Zech, S.G. / Kohlmann, A. / Zhou, T. / Li, F. / Squillace, R.M. / Parillon, L.E. / Greenfield, M.T. / Miller, D.P. / Qi, J. / Thomas, R.M. / Wang, Y. / Xu, Y. / Miret, J.J. / Shakespeare, W.C. / Zhu, X. / Dalgarno, D.C. |
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Methods | X-ray diffraction |
Resolution | 2.35 - 2.5 Å |
Structure data | ![]() PDB-5eqe: ![]() PDB-5eqp: ![]() PDB-5eqy: |
Chemicals | ![]() ChemComp-5R8: ![]() ChemComp-HOH: ![]() ChemComp-5R9: ![]() ChemComp-5RA: |
Source |
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![]() | TRANSFERASE/TRANSFERASE INHIBITOR / Kinase / inhibitor / TRANSFERASE-TRANSFERASE INHIBITOR complex / complex / drug target |