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-Structure paper
Title | Neurodegenerative disease mutations in TREM2 reveal a functional surface and distinct loss-of-function mechanisms. |
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Journal, issue, pages | Elife, Vol. 5, Year 2016 |
Publish date | Nov 4, 2015 (structure data deposition date) |
![]() | Kober, D.L. / Alexander-Brett, J.M. / Karch, C.M. / Cruchaga, C. / Colonna, M. / Holtzman, M.J. / Brett, T.J. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 3.0977 Å |
Structure data | ![]() PDB-5eli: |
Chemicals | ![]() ChemComp-NAG: |
Source |
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![]() | IMMUNE SYSTEM / Activating receptors / TREM2 / innate immunity / immune system receptor |