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-Structure paper
Title | Crystal Structures of Trimethoprim-Resistant DfrA1 Rationalize Potent Inhibition by Propargyl-Linked Antifolates. |
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Journal, issue, pages | ACS Infect Dis, Vol. 2, Page 149-156, Year 2016 |
Publish date | Oct 20, 2015 (structure data deposition date) |
Authors | Lombardo, M.N. / G-Dayanandan, N. / Wright, D.L. / Anderson, A.C. |
External links | ACS Infect Dis / PubMed:27624966 |
Methods | X-ray diffraction |
Resolution | 1.87 - 1.95 Å |
Structure data | PDB-5ecc: PDB-5ecx: |
Chemicals | ChemComp-NAP: ChemComp-6DR: ChemComp-GOL: ChemComp-CA: ChemComp-HOH: ChemComp-5N1: ChemComp-GLV: |
Source |
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Keywords | OXIDOREDUCTASE/OXIDOREDUCTASE Inhibitor / Oxidoreductase / Antifolates / dfrA1 / plasmid borne resistance / OXIDOREDUCTASE-OXIDOREDUCTASE Inhibitor complex |