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Structure paper

TitleCrystal structure of human WDR5 in complex with compound 9h
Journal, issue, pagesto be published
Publish dateOct 16, 2015 (structure data deposition date)
AuthorsDOMBROVSKI, L. / DONG, A. / SMIL, D. / GETLIK, M. / BOLSHAN, Y. / WALKER, J.R. / SENISTERRA, G. / PODA, G. / AL-AWAR, R. / SCHAPIRA, M. ...DOMBROVSKI, L. / DONG, A. / SMIL, D. / GETLIK, M. / BOLSHAN, Y. / WALKER, J.R. / SENISTERRA, G. / PODA, G. / AL-AWAR, R. / SCHAPIRA, M. / VEDADI, M. / Bountra, C. / Edwards, A.M. / Arrowsmith, C.H. / BROWN, P.J. / WU, H. / Structural Genomics Consortium (SGC)
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.8 Å
Structure data

PDB-5eal:
Crystal structure of human WDR5 in complex with compound 9h
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

Chemicals

ChemComp-5ML:
3-methyl-~{N}-[2-(4-methylpiperazin-1-yl)-5-quinolin-3-yl-phenyl]benzamide

ChemComp-GOL:
GLYCEROL

ChemComp-CL:
Unknown entry

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-UNX:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTranscription/Transcription inhibitor / WDR5 / compound 9h / Structural Genomics / Structural Genomics Consortium / SGC / Transcription-Transcription inhibitor complex

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